Cell cycle Network in FBN described in the paper 'A Novel Data-Driven Boolean Model for Genetic Regulatory Networks' (Chen, L., etc., 2018)
data(FBNcellcycleNetwork)An object of class 'list';
Chen et al.(2018), Front. Physiol., 25 September 2018, (Front. Physiol.)
data(FBNcellcycleNetwork)
FBNcellcycleNetwork
#> Fundamental Boolean Network with 10 genes
#> Genes involved:
#> CycD, Rb, E2F, CycE, CycA, p27, Cdc20, Cdh1, UbcH10, CycB
#>
#> Networks:
#> Multiple Transition Functions for CycD with decay value = 1:
#> CycD_1_Activator: CycD = CycD (Confidence: 1, TimeStep: 1)
#> CycD_1_Inhibitor: CycD = !CycD (Confidence: 1, TimeStep: 1)
#>
#> Multiple Transition Functions for Rb with decay value = 1:
#> Rb_1_Activator: Rb = !CycD&p27&!CycB (Confidence: 1, TimeStep: 1)
#> Rb_2_Activator: Rb = !CycD&!CycE&!CycA&!CycB (Confidence: 1, TimeStep: 1)
#> Rb_1_Inhibitor: Rb = CycD (Confidence: 1, TimeStep: 1)
#> Rb_2_Inhibitor: Rb = CycB (Confidence: 1, TimeStep: 1)
#> Rb_3_Inhibitor: Rb = CycA&!p27 (Confidence: 1, TimeStep: 1)
#> Rb_4_Inhibitor: Rb = CycE&!p27 (Confidence: 1, TimeStep: 1)
#>
#> Multiple Transition Functions for E2F with decay value = 1:
#> E2F_1_Activator: E2F = !Rb&!CycA&!CycB (Confidence: 1, TimeStep: 1)
#> E2F_2_Activator: E2F = !Rb&p27&!CycB (Confidence: 1, TimeStep: 1)
#> E2F_1_Inhibitor: E2F = Rb (Confidence: 1, TimeStep: 1)
#> E2F_2_Inhibitor: E2F = CycB (Confidence: 1, TimeStep: 1)
#> E2F_3_Inhibitor: E2F = CycA&!p27 (Confidence: 1, TimeStep: 1)
#>
#> Multiple Transition Functions for CycE with decay value = 1:
#> CycE_1_Activator: CycE = !Rb&E2F (Confidence: 1, TimeStep: 1)
#> CycE_1_Inhibitor: CycE = !E2F (Confidence: 1, TimeStep: 1)
#> CycE_2_Inhibitor: CycE = Rb (Confidence: 1, TimeStep: 1)
#>
#> Multiple Transition Functions for CycA with decay value = 1:
#> CycA_1_Activator: CycA = !Rb&E2F&!Cdc20&!UbcH10 (Confidence: 1, TimeStep: 1)
#> CycA_2_Activator: CycA = !Rb&CycA&!Cdc20&!UbcH10 (Confidence: 1, TimeStep: 1)
#> CycA_3_Activator: CycA = !Rb&CycA&!Cdc20&!Cdh1 (Confidence: 1, TimeStep: 1)
#> CycA_4_Activator: CycA = !Rb&E2F&!Cdc20&!Cdh1 (Confidence: 1, TimeStep: 1)
#> CycA_1_Inhibitor: CycA = Rb (Confidence: 1, TimeStep: 1)
#> CycA_2_Inhibitor: CycA = Cdc20 (Confidence: 1, TimeStep: 1)
#> CycA_3_Inhibitor: CycA = !E2F&!CycA (Confidence: 1, TimeStep: 1)
#> CycA_4_Inhibitor: CycA = Cdh1&UbcH10 (Confidence: 1, TimeStep: 1)
#>
#> Multiple Transition Functions for p27 with decay value = 1:
#> p27_1_Activator: p27 = !CycD&!CycE&!CycA&!CycB (Confidence: 1, TimeStep: 1)
#> p27_2_Activator: p27 = !CycD&!CycA&p27&!CycB (Confidence: 1, TimeStep: 1)
#> p27_3_Activator: p27 = !CycD&!CycE&p27&!CycB (Confidence: 1, TimeStep: 1)
#> p27_1_Inhibitor: p27 = CycD (Confidence: 1, TimeStep: 1)
#> p27_2_Inhibitor: p27 = CycB (Confidence: 1, TimeStep: 1)
#> p27_3_Inhibitor: p27 = CycA&!p27 (Confidence: 1, TimeStep: 1)
#> p27_4_Inhibitor: p27 = CycE&!p27 (Confidence: 1, TimeStep: 1)
#> p27_5_Inhibitor: p27 = CycE&CycA (Confidence: 1, TimeStep: 1)
#>
#> Multiple Transition Functions for Cdc20 with decay value = 1:
#> Cdc20_1_Activator: Cdc20 = CycB (Confidence: 1, TimeStep: 1)
#> Cdc20_1_Inhibitor: Cdc20 = !CycB (Confidence: 1, TimeStep: 1)
#>
#> Multiple Transition Functions for Cdh1 with decay value = 1:
#> Cdh1_1_Activator: Cdh1 = Cdc20 (Confidence: 1, TimeStep: 1)
#> Cdh1_2_Activator: Cdh1 = !CycA&!CycB (Confidence: 1, TimeStep: 1)
#> Cdh1_3_Activator: Cdh1 = p27&!CycB (Confidence: 1, TimeStep: 1)
#> Cdh1_1_Inhibitor: Cdh1 = !Cdc20&CycB (Confidence: 1, TimeStep: 1)
#> Cdh1_2_Inhibitor: Cdh1 = CycA&!p27&!Cdc20 (Confidence: 1, TimeStep: 1)
#>
#> Multiple Transition Functions for UbcH10 with decay value = 1:
#> UbcH10_1_Activator: UbcH10 = !Cdh1 (Confidence: 1, TimeStep: 1)
#> UbcH10_2_Activator: UbcH10 = Cdc20&UbcH10 (Confidence: 1, TimeStep: 1)
#> UbcH10_3_Activator: UbcH10 = UbcH10&CycB (Confidence: 1, TimeStep: 1)
#> UbcH10_4_Activator: UbcH10 = CycA&UbcH10 (Confidence: 1, TimeStep: 1)
#> UbcH10_1_Inhibitor: UbcH10 = Cdh1&!UbcH10 (Confidence: 1, TimeStep: 1)
#> UbcH10_2_Inhibitor: UbcH10 = !CycA&!Cdc20&Cdh1&!CycB (Confidence: 1, TimeStep: 1)
#>
#> Multiple Transition Functions for CycB with decay value = 1:
#> CycB_1_Activator: CycB = !Cdc20&!Cdh1 (Confidence: 1, TimeStep: 1)
#> CycB_1_Inhibitor: CycB = Cdh1 (Confidence: 1, TimeStep: 1)
#> CycB_2_Inhibitor: CycB = Cdc20 (Confidence: 1, TimeStep: 1)